4,256 hits by Charlie Hustle. Will this record ever be broken? Here's a list of active players with the best shot at reaching the record:
Derek Jeter 2,535
Alex Rodriguez 2,404
Manny Ramirez 2,392
Albert Pujols 1,531
Barring injuries, Pujols I believe has the best shot as he's only 29. A-Rod is only 33 but we can already see him breaking down.